Review Article
Genetic and Clinical Features of Multiple Endocrine Neoplasia Types 1 and 2
Table 6
Drugs used in ongoing clinical trials for the treatment of advanced MTC and other thyroid tumors.
| Drug | Molecular target |
| Axitinib | VEGFR, PDGFR, C. Kit | Gefitinib | EGFR | Imatinib | VEGFR, RET, BCR-ABL | Motesanib | VEGFR, RET, PDGFR, C. Kit | Sorafenib | VEGFR, RET, RET/PTC, BRAF, PDGFR, C. Kit | Sunitinib | VEGFR, RET, RET/PTC, PDGFR | Vandetanib | VEGFR, RET, RET/PTC, EGFR | XL184 | VEGFR, RET, PDGFR |
|
|