To Treat or Not to Treat: The Role of Adjuvant Radioiodine Therapy in Thyroid Cancer Patients

Table 5

Criteria for distinguishing low-risk and high-risk well-differentiated carcinoma based on the AGES (age, grade, extrathyroid extent, and size) classification system.

Low	High
Women < 50 years	Women ≥ 50 years
Men < 40 years	Men ≥ 40 years
Well-differentiated tumor	Poorly differentiated tumor (tall cell, columnar cell, or oxyphilic variants)
Tumor < 4 cm in diameter	Tumors ≥ 4 cm in diameter
Tumor confined to thyroid	Local invasion
No distant metastases	Distant metastases