Reactive Oxygen Species and Nitric Oxide in Cutaneous Leishmaniasis
Figure 1
Infection with L. major induces more TNF than infection with L. amazonensis. (a) TNF production by inflammatory macrophages from C57BL/10, mice infected in vitro with L. major or L. amazonensis. (b) Production of TNF ex vivo by lymph node cells from C3H/HeN, C57BL/10 and BALB/c mice infected with L. major or L. amazonensis, 2 days after infection. A biological assay that does not distinguish between TNF-α or TNF-β was used in these experiments. These are representative experiments of more than five performed experiments (L. Q. Vieira and P. Scott, unpublished).
