Nervous System of Periplaneta americana Cockroach as a Model in Toxinological Studies: A Short Historical and Actual View
Figure 4
(a) The effect of LqhαIT (10−7 M)—recombinant anti-insect alpha toxin from Leiurus quinquestriatus hebraeus venom on axonal action potential; c—control action potential, tx—progressive increase of action potential duration until plateau action potential under toxin. (b) sodium current prolonged until the end of depolarizing pulse in toxin presence (tx). (c) Repetitive discharges induced by LqhαIT (5 × 10−6 M) recorded from the axon in connective (in situ), using microelectrode technique; connective was stimulated by extracellular silver electrodes through an isolated unit. (d) Plateau action potential generated sometimes by axon in situ in toxin presence.
