Lipotoxicity: Effects of Dietary Saturated and Transfatty Acids

Figure 1

Schematic representation of SFA and TFA excess intake effects in hepatic injury and in endotoxemia. Ang II: angiotensin II, JNK: Jun N-terminal kinase, LPS: lipopolysaccharides, NF-𝜅B: nuclear factor kappa-B, Nor: Noradrenaline, ROS: reactive oxygen species, SFA: saturated fatty acids, TFA: trans fatty acids, and TNF-α: tumor necrosis factor-alpha.