Spinal Biologics in Minimally Invasive Lumbar Surgery

Table 2

Fusion rates for various bone grafts in anterior/lateral approaches to minimally invasive interbody fusions.

Bone graft materials	Anterior/lateral approaches to mis interbody fusion
	Number of studies	Number of patients	Fusion rate (%)	Range (%)
Autograft (iliac crest) alone	1	12	90	90
Allograft alone	1	40	90	90
BMA (as extender)	4	271		93–100
DBM (as extender)	2	203		97-98
Ceramics (as extender)	5	149	95	80–100
Ceramics alone	5	206	88	80–100
rhBMP-2 (with another bone graft)	7	308		80–100
rhBMP-2 alone	2	122		96–100

(as extender) demonstrates significantly higher fusion rates than all bone grafts (), except for BMA (as extender) and rhBMP-2 alone. three types of bone grafts (BMA as extender, rhBMP-2 with another bone graft, and rhBMP-2 alone) are no different from each other and DBM in terms of fusion rate but significantly better than the rest ().