[Retracted] Consensus Guidelines for CSF and Blood Biobanking for CNS Biomarker Studies

Table 1

Results of inventory on collection protocols among 14 MS Biomarker Research Centers.

Procedure of CSF withdrawal	Previous status among European CSF centers
Type of needle:	71% atraumatic, 21% traumatic, 8% both
Time of the day of withdrawal (important for markers that are sensitive for circadian rhythm)	71% no specific day/time of withdrawal, 29% in the afternoon only
Temperature until storage	57% room temperature, 43% at 4°C
Type of tube:	50% Sarstedt, 29% Eppendorf, 21% other
aliquoting:	Range from 0.2 mL to 2 mL
(1) surveillance of freezers	Present at 93% of the centers
(2) several freezers to split the samples (backup)	Present at 14% of the centers