Neuroimaging of Natalizumab Complications in Multiple Sclerosis: PML and Other Associated Entities

<div>63-year-old woman with MS presenting with profound neurologic deterioration. (a) FLAIR image demonstrates characteristic PML lesions involving the subcortical U-fibers which also extent centrally to the periventricular surface. (b) T2-weighted image on the same patient demonstrates “granular” or “microcystic” foci (arrows).</div>

Multiple Sclerosis International

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Figure 3

Figure 3: Neuroimaging of Natalizumab Complications in Multiple Sclerosis: PML and Other Associated Entities 