Neuroimaging of Natalizumab Complications in Multiple Sclerosis: PML and Other Associated Entities

Figure 7

(a) T2 FLAIR and (b) DWI images demonstrate a large PML lesion. (b) DWI demonstrates cytotoxic edema along the advancing edge of the lesion (arrows) surrounding the quiescent center. (c) Repeat MR DWI image following PLEX demonstrates absence of the hyperintense rim suggesting that disease progression has resolved.

(a)

(b)

(c)