Review Article
Review of Small Cell Carcinomas of the Prostate
Table 1
Immunohistochemical findings of small cell carcinoma of the prostate compared with conventional high-grade adenocarcinomas [
6,
8,
10,
17,
20,
30–
35].
| Antibody | Small cell carcinoma | Poorly differentiated | (approximate | adenocarcinoma | percentage of | (approximate percentage | positivity) | of positivity) |
| Cytokeratin | (94%) | + (70%) | Cytokeratin high | (35%) −/+ | − (0-33%) | molecular weight | CAM 5.2 | (72%) | + (90%) | CK 7 | (39%) −/+ | −/+ (30%) | CK 20 | (11%) −/+ | −/+ (10%) | PSA | (24%) −/+ | ++ (85%) | PSMA | (20%) −/+ | ++ (90%) | PSAP | (22%) −/+ | ++ (95%) | P501s | (25%) −/+ | ++ (90%) | p63 | (40%) −/+ | −−/+ (15%) | TTF1 | (83%) +/− | − (10%) | CD 56 | (92%) + | − (10%) | Chromogranin | (80%) + | − (10%) | Synaptophysin | (85%) + | −/+ (13%) | CD44 | (60-96%) ++ | − (5%) |
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