Review of Small Cell Carcinomas of the Prostate

Table 1

Immunohistochemical findings of small cell carcinoma of the prostate compared with conventional high-grade adenocarcinomas [6, 8, 10, 17, 20, 30–35].

Antibody	Small cell carcinoma	Poorly differentiated
	(approximate	adenocarcinoma
	percentage of	(approximate percentage
	positivity)	of positivity)
Cytokeratin	(94%)	+ (70%)
Cytokeratin high	(35%) −/+	− (0-33%)
molecular weight
CAM 5.2	(72%)	+ (90%)
CK 7	(39%) −/+	−/+ (30%)
CK 20	(11%) −/+	−/+ (10%)
PSA	(24%) −/+	++ (85%)
PSMA	(20%) −/+	++ (90%)
PSAP	(22%) −/+	++ (95%)
P501s	(25%) −/+	++ (90%)
p63	(40%) −/+	−−/+ (15%)
TTF1	(83%) +/−	− (10%)
CD 56	(92%) +	− (10%)
Chromogranin	(80%) +	− (10%)
Synaptophysin	(85%) +	−/+ (13%)
CD44	(60-96%) ++	− (5%)