Pulmonary Hypertension Related to Left-Sided Cardiac Pathology

Table 1

Classification system of pulmonary hypertension into groups 1–5 based on underlying disease process.

Group 1	Group 1′	Group 2	Group 3	Group 4	Group 5
(i) Idiopathic; (ii) Familial; (iii) Connective tissue diseases; (iv) Congenital shunt lesions; (v) HIV; (vi) Drugs/Toxins; (vii) Hemoglobinopathies; (viii) Portal hypertension; (ix) Persistent pulmonary hypertension of the newborn	PVOD	(i) Left ventricular systolic/diastolic dysfunction; (ii) Left-sided valvular dysfunction	Chronic lung diseases and/or hypoxemia	Chronic thromboembolic disease	Miscellaneous; (i) Sarcoid; (ii) Histiocytosis X; (iii) Fibrosing mediastinitis; (iv) Myeloproliferative disorders; (v) Metabolic storage diseases; (vi) Thyroid disease