Review Article
Pulmonary Hypertension Secondary to COPD
Table 2
Comparison of 2 groups of COPD patients with PH.
| | | Severe PH Group (mPAP ≥ 40 mm Hg) N = 11 | Less severe PH (mPAP 20–40 mm Hg) N = 16 | P value |
| | FEV1 (% predicted) | 50 (44–56) | 27 (23–34) | <0.01 | | DLCO (mL/min/mm Hg) | 4.6 (4.2–6.7) | 10.3 (8.9–12.8) | <0.01 | | PaO2 (mm Hg) | 46 (41–53) | 56 (54–64) | <0.01 | | PaCO2 (mm Hg) | 32 (28–37) | 47 (44–49) | <0.01 | | RAP (mm Hg) | 7 (5–9) | 3 (1.3–4) | <0.01 | | mPAP (mm Hg) | 48 (46–50) | 25 (22–27) | <0.01 | | PAWP (mm Hg) | 6 (4–7) | 7 (6.5-7.5) | NS | | CI (L/min/m2) | 2.3 (1.8–2.5) | 2.8 (2.4–3.1) | <0.01 | | TPR (Wood units/m2) | 21.3 (17.6–26.6) | 9 (7.4–9.9) | <0.01 |
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Table adapted from [63].
PH: pulmonary hypertension, FEV1: forced expiratory volume in the first second, DLCO: diffusing capacity for carbon monoxide, PaO2: arterial oxygen tension, PaCO2: arterial carbon dioxide tension, RAP: right atrial pressure, mPAP: mean pulmonary artery pressure, CI: cardiac index, TPR: total pulmonary resistance.
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