Interactions between PPAR Gamma and the Canonical Wnt/Beta-Catenin Pathway in Type 2 Diabetes and Colon Cancer

Figure 2

A schematic representation of interactions between PPAR gamma and the canonical Wnt/beta-catenin pathway in type 2 diabetes and colon cancer. Green arrow: activation; red arrow: inhibition; abbreviations are as follows: acetyl-CoA (A-CoA); glucokinase (GK); glucose transporter (GLUT); intracellular lactate (IC lactate); extracellular lactate (EC lactate); lactate dehydrogenase-A (LDH-A); monocarboxylate lactate transporter-1 (MCT-1); pyruvate dehydrogenase (PDH); pyruvate dehydrogenase kinase (PDK); peroxisome proliferator-activated receptor gamma (PPAR gamma).