Review Article
Crosstalk between MicroRNAs and Peroxisome Proliferator-Activated Receptors and Their Emerging Regulatory Roles in Cardiovascular Pathophysiology
Figure 1
The regulation of peroxisome proliferator-activated receptors (PPARs) by microRNAs in pulmonary hypertension. PASMC: pulmonary arterial smooth muscle cells; PAEC: pulmonary arterial endothelial cells; PTEN: phosphatase and tensin homolog deleted on chromosome 10; PDCD4: programmed cell death 4; STAT3: signal transducer and activator of transcription 3; EDN1: endothelin-1; APOE: apolipoprotein E; NO: nitric oxide; eNOS: EC nitric oxide synthase.