Improved Left Ventricular Diastolic Function with Exercise Training in Hypertension: A Doppler Imaging Study

Table 4

Doppler echocardiographic parameters at baseline and after 6 months in the 2 patient groups.

	Exercise group		Control group		𝑃-value
	𝑛=25		𝑛=25
	Baseline	6 months	Baseline	6 months
LAVI (ml/m^2)	35.1 (4.2)	32.3 (3.8)	35.7 (3.9)	35.9 (4.2)	.017
LVDd (mm)	47.4 (5.5)	46.9 (6.1)	48.1 (3.3)	48.3 (4.0)	.592
LVSd (mm)	32.4 (2.6)	33.1 (2.8)	32.8 (2.4)	33.1 (3.1)	.273
IVST (mm)	10.8 (0.9)	10.5 (1.0)	11.1 (0.7)	10.9 (0.9)	.269
PVST (mm)	10.3 (0.4)	10.2 (0.5)	10.4 (0.3)	10.4 (0.6)	.727
LVEF (%)	54.5 (5.5)	55.1 (6.2)	55.0 (4.9)	54.8 (4.6)	.614
E/A	0.75 (0.07)	0.88 (0.06)	0.72 (0.05)	0.70 (0.07)	.004
DT (ms)	220 (14)	242 (18)	226 (20)	218 (19)	.018
IVRT (ms)	109 (12)	89 (11)	106 (14)	109 (13)	.037
S/D	1.4 (0.2)	1.1 (0.3)	1.5 (0.2)	1.2 (0.2)	.008
Ea/Aa [1]	0.87 (0.26)	1.12 (0.28)	0.90 (0.24)	0.96 (0.30)	.019
Ea/Aa [2]	0.92 (0.18)	1.20 (0.24)	0.89 (0.17)	0.87 (0.25)	.006
Ea/Aa [3]	0.85 (0.17)	1.05 (0.23)	0.86 (0.23)	0.86 (0.19)	.028
Ea/Aa [4]	0.96 (0.16)	1.21 (0.18)	0.96 (0.27)	0.93 (0.29)	.036
Mean Ea/Aa	0.89 (0.23)	1.19 (0.21)	0.91 (0.23)	0.90 (0.24)	.011

LAVI: left atrial volume index; LVDd: left ventricular end-diastolic diameter; LVSd: left ventricular end-systolic diameter; IVST: interventricular septum thickness in diastole; PVST: posterior ventricular septum thickness in diastole; LVEF: left ventricular ejection fraction; E: early diastolic mitral inflow peak velocity; A: late diastolic mitral inflow peak velocity; DT: deceleration time of the mitral E wave; IVRT: isovolumic relaxation time; S/D: systolic velocity to diastolic velocity ratio by pulmonary veins; Ea: early diastolic myocardial peak velocity; Aa: late diastolic myocardial peak velocity; Ea/Aa [1], Ea/Aa [2], Ea/Aa [3], and Ea/Aa [4] refer to Ea/Aa ratio at septum mitral annulus, lateral mitral annulus, interventricular medium septum, and lateral medium wall, respectively; meanEa/Aa = (Ea/Aa [1] + Ea/Aa [2] + Ea/Aa [3] + Ea/Aa [4])/4.