Premature Calcifications of Costal Cartilages: A New Perspective

Table 1

Selected clinical findings in 19 patients with premature calcifications of the costal cartilages.

Number	Age/Sex	Metabolic disorders	Diseases of endocrine organs	Laboratory data (increases)
1	30/M		Testicular fibrosis, azoospermia
2	19/F	Acute intermittent porphyria		Delta-ALS + porphobilinogen
3	22/F		Mayer-von Rokitansky-Küster syndrome
4	20/F	Suspected porphyria	Ovarian teratomas, bilateral	*
5	25/F	Glucosuria, cholelithiasis
6	26/F		Morbus Addison
7	30/F	None	None
8	20/F		Hyperthyroidism, goiter oligomenorrhea
9	31/F	Suspected porphyria		17-OH-steroids^*
10	27/F	Suspected porphyria	Microcystic degeneration of the right ovary	Porphobilinogen
11	30/M		Morbus Addison, inherited
12	28/F	Decreased 17-keto- and 17-OH-steroids	Bilateral ovarian cysts	Delta-ALS + coproporphyrin
13	23/F	Orotic aciduria, suspected porphyria		*
14	27/F	Cholelithiasis
15	30/F	Suspected porphyria		*
16	26/F	Cholelithiasis
17	29/F	Suspected porphyria	Oligomenorrhea	*
18	30/F	Suspected porphyria	Ovarian cysts, follicular	*
19	27/F	Porphyria, unspecified	Hypothyroidism

ALS: delta-aminolevulinic acid; no lab screening as to porphyria done.