Adipose-Derived Stem Cells: Current Applications and Future Directions in the Regeneration of Multiple Tissues

Figure 3

Flow chart of the experimental steps for long-term cartilage repair in rabbits (a). Immunohistochemical staining of interleukin- (IL-) 1β, IL-6, IL-10, and tumor necrosis factor (TNF). Black solid arrows denote the positive expression of IL-6 in the repair interface (b). Histological analysis of the cartilage defect after 3 and 6 months by hematoxylin and eosin (H&E) staining. Black solid arrows denote the repair interface. Red solid arrows denote the depth of the repaired cartilage (c). HC: host cartilage; RC: repaired cartilage. Adapted from a previous study [84], with permission.

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