CPAP Treatment Partly Normalizes Sleep Spindle Features in Obstructive Sleep Apnea

Table 5

Median and range of the spindle features in the study groups at the last part of the NREM time.

	Controls		Pre-CPAP		CPAP		Controls versus; pre-CPAP	Controls; versus CPAP	Pre-CPAP versus CPAP
	Median	Range	Median	Range	Median	Range	value	value	value
Density /h
Bil Fp dens	43.7	7.3–110.3	23.2	0.5–105.7	23.6	1.1–102.6	0.350	0.533	1.0
Fp2 dens	85.1	26.6–136.9	52.5	10.6–157-7	54.4	10.1–159.3	0.768	1.0	0.741
Fp1 dens	65.6	15.9–150.5	43.8	7.1–141.3	46.4	12.7–129.0	0.223	0.518	0.033
Bil C dens	76.5	18.3–215.7	32.6	0.5–282.5	35.4	4.4–282.0	0.010	0.018	0.436
C4 dens	111.5	63.8–183.5	78.2	21.6–196.8	90.1	18.6–191.8	0.223	0.626	0.027
C3 dens	117.1	46.4–229.7	64.3	20.2–231.6	85.4	26.9–217.7	0.033	0.093	0.238
Frequency Hz
Bil Fp2 freq	11.7	11.1–12.4	11.6	11.0–13.6	11.3	10.8–13.0	1.0	0.074	0.001
Bil Fp1 freq	11.8	11.1–12.4	11.6	10.8–13.3	11.4	10.7–13.0	1.0	0.243	0.131
Fp2 freq	11.7	11.2–12.4	11.7	10.9–13.0	11.5	11.0–12.8	1.0	0.395	0.022
Fp 1 freq	11.9	11.2–12.4	11.6	11.1–13.0	11.4	11.0–12.9	0.640	0.159	0.037
Bil C4 freq	13.1	11.4–14.3	13.3	10.8–14.9	13.0	10.9–14.6	1.0	1.0	0.007
Bil C3 freq	13.1	11.2–14.3	13.3	10.8–14.8	12.8	10.9–14.8	0.912	1.0	0.004
C4 freq	12.9	11.2–14.1	12.6	11.0–14.5	12.5	10.9–13.9	1.0	1.0	0.041
C3 freq	12.8	11.1–14.3	13.0	10.9–15.0	12.4	10.9–13.9	1.0	1.0	0.005
Sequences %
Fp sequences	0.0	0.0–0.5	0.0	0.0–0.5	0.0	0.0–0.5	1.355	1.0	0.999
C sequences	0.6	0.0–4.0	0.1	0.0–7.3	0.0	0.0–7.1	0.086	0.097	1.0
Bilaterality indices
Fp bil index 1	0.47	0.15–1.22	0.36	0.04–0.73	0.43	0.11–0.75	0.168	0.388	1.0
Fp bil index 2	0.61	0.15–1.07	0.48	0.04–1.15	0.46	0.09–1.05	0.506	0.191	1.0
C bil index 1	0.79	0.17–1.55	0.36	0.03–1.44	0.42	0.14–1.47	0.006	0.008	1.0
C bil index 2	0.72	0.20–1.38	0.45	0.03–1.22	0.36	0.15–1.30	0.015	0.009	1.0

Mann-Whitney test; Wilcoxon test. The Bonferroni corrected values are reported: Bonferroni correction factor = 3.
Abbreviations as in Table 2.