Research Article

Comparative Study of Metaheuristics for the Curve-Fitting Problem: Modeling Neurotransmitter Diffusion and Synaptic Receptor Activation

Table 18

Raw values (NLLS unconstrained is the control algorithm) for the 9th degree polynomial.

NLLS unconstrained versus Friedman value Wilcoxon value

Self-Adaptive DE
DE
NLLS constrained
IPOP-CMA-ES
GA
Solis and Wets
MTS-LS1
GODE