Research Article

Comparative Study of Metaheuristics for the Curve-Fitting Problem: Modeling Neurotransmitter Diffusion and Synaptic Receptor Activation

Table 20

Mean fitness, average ranking, and number of wins (nWins) in pair-wise comparisons with the other algorithms for all the models.

Mean fitness Ranking nWins

IPOP-CMA-ES 2.44 8
Self-Adaptive DE 2.86 6
DE 3.62 4
NLLS unconstrained 4.74 2
NLLS constrained 5.46 0
GA 5.83 −2
GODE 5.93 −4
MTS-LS1 6.61 −6
Solis and Wets 7.50 −8