Research Article

A Computational Study of HSV-2 with Poor Treatment Adherence

Table 1

Model parameters and their baseline values. The time unit is in months.

Definition Symbol Baseline values Source

Reactivation rate with an effect of treatment Varying [9]
Proportion of HSV-2 patients who successfully complete treatment0.7 (0-1)Estimate
Effective contact rate for HSV-2 infection 0.2 [9, 18]
Baseline reactivation rate of latent HSV-2 0.3875 (0.339–0.436) [19]
Rate of acute HSV-2 becoming latent 2.3805 (2.083–2.678) [19]
Treatment rate of acute HSV-2 Varied [9]
Average sexual lifespan 0.0004 (0.003–0.005) [18, 19]
Modification parameter 0.4 (0-1) Estimate
Treatment quitting rate 0.3 [20, 21]