Fluid-Solid Coupling Simulation of Wall Fluid Shear Stress on Cells under Gradient Fluid Flow

Figure 2

Analytical method of wall FSS on cell surface. (a) Mesh dependency analysis. (b) FE mesh and wall FSS of gradient flow chamber. (c) Numerical simulation results of wall FSS on the bottom plate at the location indicated by the red box in (b). (d) Wall FSS of all nodes at different FSS gradients and linearly fitted by the dotted line. (e) Fluid velocity of the locations with the same height of 0.4 mm and two different x positions. (f) Dorsal surface of a cell divided into four sectors, including the sectors with higher global FSS (SHFSS) and lower global FSS (SLFSS). (g) Bands on the cell surface with three orientations, i.e., 30°, 45°, and 60°. (h) Top views of the bands with different orientations in the sectors.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)