Review Article

Recent Applications of Electrospun Nanofibrous Scaffold in Tissue Engineering

Table 1

Effects of electrospinning parameters on the morphology of electrospun fibers.

ParameterEffect of parameter on fiber morphology

Viscosity/concentrationFiber diameters increased with increasing concentration/viscosity.
Applied voltageThe relationship between voltage and fiber diameter was difficult to ascertain.
Distance between nozzle and collectorTo acquire dry fibers, a minimum distance was needed. Also, beading was seen at either too close or too far distances.
Flow rateFibers with smaller diameters were produced at lower flow rates, and excessive flow rates resulted in fibers that were not dry when they arrived at the collector.
Solution conductivityIn general, higher conductivities resulted in smaller fibers, but increasing conductivity facilitated in the creation of bead-free fibers that were consistent.
Ambient parametersAs the temperature rose, the viscosity of the solution decreased, resulting in smaller fibers. Increasing humidity caused the fibers to develop circular pores.
Surface tensionAs the surface tension coefficient of the solutions increased, the quantity of beads increased.