Research Article

[Retracted] Abnormal GRHL2 Methylation Confers Malignant Progression to Acute Leukemia

Table 3

Univariate and multivariate analysis of overall survival in patients with acute leukemia ().

CharacteristicsUnivariate analysisMultivariate analysis
HR95% CIHR95% CI

Gender0.65
 Male vs. female0.8090.324-2.023
Ages (years)0.654
 ≤60 vs. >601.2820.434-3.787
WBC count0.277
vs. 1.9130.593-6.166
Platelet count (109/L)0.63
vs. 1.3190.428-4.064
Bone marrow blast cell (%)0.325
 ≥30% vs. <30%1.4670.684-3.147
FAB classification0.42
 M0 vs. M1 vs. M2 vs. M3 vs. M4 vs. M5 vs. M6 vs. M71.1180.853-1.466
Cytogenetic risk group0.292
 Favorable vs. intermediate vs. unfavorable1.3340.781-2.277
Hemoglobin (g/L)0.0440.077
 >90 g/L vs. ≤90 g/L0.3390.119-0.9710.5270.259-1.071
GRHL2 expression0.0050.03
 Low vs. high2.8361.373-5.8600.3310.159-0.689

Abbreviations: HR: hazard ratio; CI: confidence interval.