Research Article
[Retracted] Abnormal GRHL2 Methylation Confers Malignant Progression to Acute Leukemia
Table 3
Univariate and multivariate analysis of overall survival in patients with acute leukemia (
).
| Characteristics | Univariate analysis | Multivariate analysis | HR | 95% CI | | HR | 95% CI | |
| Gender | | | 0.65 | | | | Male vs. female | 0.809 | 0.324-2.023 | | | | | Ages (years) | | | 0.654 | | | | ≤60 vs. >60 | 1.282 | 0.434-3.787 | | | | | WBC count | | | 0.277 | | | | vs. | 1.913 | 0.593-6.166 | | | | | Platelet count (109/L) | | | 0.63 | | | | vs. | 1.319 | 0.428-4.064 | | | | | Bone marrow blast cell (%) | | | 0.325 | | | | ≥30% vs. <30% | 1.467 | 0.684-3.147 | | | | | FAB classification | | | 0.42 | | | | M0 vs. M1 vs. M2 vs. M3 vs. M4 vs. M5 vs. M6 vs. M7 | 1.118 | 0.853-1.466 | | | | | Cytogenetic risk group | | | 0.292 | | | | Favorable vs. intermediate vs. unfavorable | 1.334 | 0.781-2.277 | | | | | Hemoglobin (g/L) | | | 0.044 | | | 0.077 | >90 g/L vs. ≤90 g/L | 0.339 | 0.119-0.971 | | 0.527 | 0.259-1.071 | | GRHL2 expression | | | 0.005 | | | 0.03 | Low vs. high | 2.836 | 1.373-5.860 | | 0.331 | 0.159-0.689 | |
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Abbreviations: HR: hazard ratio; CI: confidence interval.
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