257512.fig.005a
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257512.fig.005b
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257512.fig.005c
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Figure 5: Each time a hub appears in an SSE-IN, we sum its degree according to the amino acid it represents. We repeat the process grouping the SSE-IN by their family and also by their structural class. We normalization to obtain the cumulative connectivity by class. The amino acid Ala acts more often as hub independently of the protein classifications.