Research Article

Designing Efficient Spaced Seeds for SOLiD Read Mapping

Table 2

Comparison of 6 read-mapping tools on S. cerevisiae dataset. The execution time refers to all steps, including index construction for the tools that can reuse the result of this step (Bowtie, BWA, MAQ).

Program Mapped reads Unique mapping positions Execution time

Bowtie 553,140 (43.20%) 512,086 (39.99%) 0m50s
BWA 422,550 (33.00%) 395,342 (30.87%) 0m38s
MAQ 616,497 (48.14%) 567,549 (44.32%) 1m20s
PerM 418,524 (32.68%) 347,668 (27.15%) 0m31s
SHRiMP 1.3.2 663,923 (51.85%)ā€”7m56s
SHRiMP 2.0 709,146 (55.38%)ā€”1m22s
STORM 839,633 (65.57%) 754,402 (58.91%) 2m10s