Analytical Cellular Pathology

Analytical Cellular Pathology / 2012 / Article

Review Article | Open Access

Volume 35 |Article ID 904828 |

Richard Levenson, Joseph Beechem, George McNamara, "Modern Trends in Imaging X: Spectral Imaging in Preclinical Research and Clinical Pathology", Analytical Cellular Pathology, vol. 35, Article ID 904828, 23 pages, 2012.

Modern Trends in Imaging X: Spectral Imaging in Preclinical Research and Clinical Pathology


Spectral imaging methods are attracting increased interest from researchers and practitioners in basic science, pre-clinical and clinical arenas. A combination of better labeling reagents and better optics creates opportunities to detect and measure multiple parameters at the molecular and cellular level. These tools can provide valuable insights into the basic mechanisms of life, and yield diagnostic and prognostic information for clinical applications. There are many multispectral technologies available, each with its own advantages and limitations. This chapter will present an overview of the rationale for spectral imaging, and discuss the hardware, software and sample labeling strategies that can optimize its usefulness in clinical settings.

Copyright © 2012 Hindawi Publishing Corporation and the authors. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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