Observer Performance in the Use of Digital and Optical Microscopy for the Interpretation of Tissue-Based Biomarkers

Table 3

Intermodality (optical versus digital) agreement in the assessment of HER2 with whole slides and TMA using Kendall’s tau- metric [95% CI].

Intermodality HER2	Kendall’s tau- on continuous scores	Kendall’s tau- on categorical scores
Whole slides	0.73 [0.56–0.85]	0.72 [0.54–0.84]
TMA	0.83 [0.76–0.89]	0.83 [0.76–0.88]