Table of Contents Author Guidelines Submit a Manuscript
Analytical Cellular Pathology
Volume 2014, Article ID 343461, 6 pages
Research Article

Cytologic-Radiologic Correlation Using Transthoracic CT-Guided FNA for Lung and Mediastinal Masses: Our Experience

1Department of Pathology, Sri Guru Ram Das Institute of Medical Sciences & Research, 24 Lane No. 5, Gopal Nagar, Majitha Road, Amritsar, Punjab 143001, India
2Department of Anatomy, Sri Guru Ram Das Institute of Medical Sciences & Research, Amritsar, Punjab, India

Received 11 June 2014; Accepted 14 September 2014

Copyright © 2014 Sanjay Piplani et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background and Objectives. Thoracic lesions account for various benign and malignant conditions. Of these lung carcinoma (mainly primary) is the most common carcinoma in the world. The present study was undertaken to know the pathological spectrum of thoracic lesions and to correlate cytoradiological findings. Materials and Methods. The present study was conducted in a tertiary care center of North India on 74 patients over an 18-month period. CT guided transthoracic FNAC (TTFNA) was carried out, and aspirates were drawn, examined, and compared with radiological diagnoses. Results. The diagnostic accuracy for FNA in the present study was calculated to be 95.94% (using cytology as the gold standard). The predominant lesion was malignancy (85.1%), followed by suspicions of malignancy and inflammatory pathology (5.40% each). By cytology, the most common malignant lesion was adenocarcinoma (48%) followed by squamous cell carcinoma (40%), small cell carcinoma (8%), and undifferentiated carcinoma (4%). Cytoradiological correlation was found to be 89.2% in the present study. Conclusion. Present study thus concludes that TT FNA of thoracic lesions is a simple, safe, economically prudent technique associated with low morbidity and leading to quick and early diagnosis.