Research Article

A Comparative and Evaluative Study of Two Cytological Grading Systems in Breast Carcinoma with Histological Grading: An Important Prognostic Factor

Figure 3

Infiltrating ductal carcinoma histological grade III—very minimal tubular differentiation, marked nuclear pleomorphism, coarse nuclear chromatin, prominent nucleoli, and brisk mitosis. Inset—highly pleomorphic tumor cells with marked nucleomegaly (>5 times the size of erythrocytes), irregular nuclear membrane, prominent nucleoli, and coarsely clumped chromatin (Robinson’s cytological grade III) (H&E, ×200; inset: PAP, ×400).