A Comparative and Evaluative Study of Two Cytological Grading Systems in Breast Carcinoma with Histological Grading: An Important Prognostic Factor

Figure 4

(a) Loosely cohesive cluster of mild pleomorphic ductal epithelial cells with mild nucleomegaly, smooth nuclear envelope, and indistinct nucleoli—Robinson’s cytological grade I (PAP, ×400). (b) Moderately pleomorphic ductal cells with slightly irregular nuclear membrane and noticeable nucleoli. Nuclei are 3-4 times the size of erythrocytes—Robinson’s cytological grade II (PAP, ×400). (c and d) Robinson’s cytological grade III—markedly pleomorphic discohesive singly scattered tumor cells with marked nucleomegaly, irregular nuclear membrane, prominent abnormal nucleoli, and coarsely clumped nuclear chromatin ((c) PAP, ×400; (d) PAP, ×400).