Melatonin Modulates Endoplasmic Reticulum Stress and Akt/GSK3-Beta Signaling Pathway in a Rat Model of Renal Warm Ischemia Reperfusion

Figure 2

Representative histological photographs of kidney tissues from Sham (a), I/R (b), and Mel + I/R (c) groups (H&E) ×400. Semiquantitative assessment of renal necrosis among the different experimental groups using the Jablonski score (d). The arrows denote brush border loss, “H” denotes hemorrhage, and “L” denotes nuclei loss. Results are expressed as mean ± SEM ( for each group). versus Sham. versus I/R.

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