Diphenyl Ditelluride Intoxication Triggers Histological Changes in Liver, Kidney, and Lung of Mice

Figure 3

Liver histological analysis of mice exposed to diphenyl ditelluride 50 μmol/kg for 7 days. (a) Liver section of control group showing polygonal hepatocytes with oval shaped nuclei, dispersed chromatin, and prominent nucleolus cordially arranged towards hepatic central vein (detail in 40x); (b) liver section of diphenyl ditelluride treated mice showing hepatocytes with manifestation of hydropic degeneration (detail in 40x); (c) pyknotic nuclei and eosinophilic cytoplasm (arrow) (detail in 40x) and (d) mononuclear infiltrate in centrilobular (zone 3) and mediolobular (zone 2) (arrow) areas (H&E 10x). The picture is a representation of three independent experiments.

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