Diphenyl Ditelluride Intoxication Triggers Histological Changes in Liver, Kidney, and Lung of Mice

Figure 4

Liver histological analysis of mice acutely exposed to diphenyl ditelluride 250 μmol/kg. (a) Liver section of control group showing preserved polygonal hepatocytes with oval-shaped nuclei, dispersed chromatin, and prominent nucleolus cordially arranged towards hepatic central vein; (b) liver section of diphenyl ditelluride treated mice showing microvesicular steatosis and macrovesicular steatosis; (c) presence of sinusoidal dilatation mainly in centrilobular and mediolobular areas; (d) hepatocytes with pyknotic nuclei surrounded area with vascular congestion and hepatic laminae disorganized (H&E 10x). The picture is a representation of three independent experiments.

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