Low-Dose Ribavirin Treatments Attenuate Neuroinflammatory Activation of BV-2 Cells by Interfering with Inducible Nitric Oxide Synthase
Morphology of BV-2 cells upon 24 h of LPS stimulation and RBV treatment. Phalloidin/Hoechst fluorescent staining (red/blue) of control (a), LPS (b), and LPS stimulated BV-2 cells treated with 0.1 (c), 1 (d), and 10 μM RBV (e). (f) Cell surface area was measured using AxioVision Rel. 4.6 software, in five areas (138 × 104 μm2) per each coverslip () per experimental group in three independent experiments. Bars represent mean surface areas (±SEM) obtained from data presented in (a)–(e). versus control group, versus LPS stimulated group. Scale bar (a)–(e): 50 μm.
Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.