PECAM-1 Leu125Val (rs688) Polymorphism and Diabetic Nephropathy in Caucasians with Type 2 Diabetes Mellitus

Table 3

Logistic regression analysis adjusted for different confounders (duration of hypertension, systolic blood pressure, CVD, diabetic retinopathy, diabetic foot, HbA1c, fasting glucose, urea, creatinine, cystatin C, and urine albumin/creatinine ratio) according to codominant genetic model.

Inheritance; model	Genotype	Cases (276)	Controls (375)	Unadjusted OR, 95% CI/ value	Adjusted OR, 95% CI/ value
rs668	GG	56 (20.4)	64 (17.0)	1.42 (0.89–2.24)/0.1	0.85 (0.34–2.11)/0.7
Codominant	GC	144 (52.0)	189 (50.3)	1.23 (0.86–1.75)/0.3	1.65 (0.83–3.26)/0.9
	CC	76 (27.6)	122 (32.7)	Reference	Reference

values were adjusted for duration of hypertension, SBP, CVD, DR, DF, haemoglobin , haemoglobin A1C (HbA1c), S-fasting glucose, S-urea, S-creatinine, S-cystatin, and U-albumin/creatinine ratio [g/mol], sample no. 1–no. 3.
Odds ratio (OR); confidence interval (CI).