Analytical Cellular Pathology / 2017 / Article / Tab 1

Clinical Study

The Efficacy of Neoadjuvant Chemotherapy for HER-2-Positive Locally Advanced Breast Cancer and Survival Analysis

Table 1

Univariate analysis of factors associated with pCR.

CharacteristicNon-pCRpCRΧ2

Age (year)≤401520.0130.910
>408913

Histological typeInvasive ductal99150.7530.386
Invasive papillary50

Histological grade27991.7340.188
3256

ER statusNegative5460.7450.388
Positive509

PR statusNegative7164.5870.032
Positive339

Ki67≤30%7064.20.040
>30%349

Primary tumor size preoperationcT10115.7480.001
cT2279
cT3424
cT4351

Regional lymph node preoperationcN0301.380.710
cN1235
cN2283
cN3507

Clinical stage preoperationIIA2010.3680.035
IIB54
IIIA354
IIIB110
IIIC517

Treatment regimenTEC4952.7840.733
EC-T41
TCH132
EC-TH266
Replacement single chemotherapy60
Replacement chemotherapy + H61

Trastuzumab cycle preoperation059611.4180.044
2-3131
4196
501
6111
820

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