Different Cytokine and Chemokine Expression Patterns in Malignant Compared to Those in Nonmalignant Renal Cells

Table 1

Human Cytokines & Chemokines RT² Profiler PCR Array (Qiagen). Abbreviation (symbol) and full name/function (description) of the 84 cytokines and chemokines analyzed by the PCR array. The column “detectable” indicates whether the factor was detected (+) or not detected (−) within this study.

Number	Symbol	Description	Detectable
Chemokines
1	C5	Complement component 5	+
2	CCL1	Chemokine (C-C motif) ligand 1	−
3	CCL2	Chemokine (C-C motif) ligand 2	+
4	CCL3	Chemokine (C-C motif) ligand 3	−
5	CCL5	Chemokine (C-C motif) ligand 5	+
6	CCL7	Chemokine (C-C motif) ligand 7	+
7	CCL8	Chemokine (C-C motif) ligand 8	−
8	CCL11	Chemokine (C-C motif) ligand 11	+
9	CCL13	Chemokine (C-C motif) ligand 13	+
10	CCL17	Chemokine (C-C motif) ligand 17	−
11	CCL18	Chemokine (C-C motif) ligand 18	−
12	CCL19	Chemokine (C-C motif) ligand 19	−
13	CCL20	Chemokine (C-C motif) ligand 20	+
14	CCL21	Chemokine (C-C motif) ligand 21	+
15	CCL22	Chemokine (C-C motif) ligand 22	−
16	CCL24	Chemokine (C-C motif) ligand 24	−
17	CXCL1	Chemokine (C-X-C motif) ligand 1	+
18	CXCL2	Chemokine (C-X-C motif) ligand 2	+
19	CXCL5	Chemokine (C-X-C motif) ligand 5	+
20	CXCL9	Chemokine (C-X-C motif) ligand 9	−
21	CXCL10	Chemokine (C-X-C motif) ligand 10	+
22	CXCL11	Chemokine (C-X-C motif) ligand 11	+
23	CXCL12	Chemokine (C-X-C motif) ligand 12	+
24	CXCL13	Chemokine (C-X-C motif) ligand 13	−
25	CXCL16	Chemokine (C-X-C motif) ligand 16	+
26	CX3CL1	Chemokine (C-X3-C motif) ligand 1	+
27	GPI/AMF	Glucose-6-phosphate isomerase	+
28	IFNA2	Interferon, alpha 2	+
29	MIF	Macrophage migration inhibitory factor	+
30	PPBP	Proplatelet basic protein (chemokine (C-X-C motif) ligand 7)	+
31	SPP1	Secreted phosphoprotein 1	+
32	XCL1	Chemokine (C motif) ligand 1	−
Growth factors
33	BMP2	Bone morphogenetic protein 2	+
34	BMP4	Bone morphogenetic protein 4	+
35	BMP6	Bone morphogenetic protein 6	+
36	BMP7	Bone morphogenetic protein 7	−
37	CNTF	Ciliary neurotrophic factor	+
38	CSF1	Colony stimulating factor 1 (macrophage)	+
39	CSF2	Colony stimulating factor 2 (granulocyte-macrophage)	+
40	CSF3	Colony stimulating factor 3 (macrophage)	+
41	LIF	Leukemia inhibitory factor (cholinergic differentiation factor)	+
42	MSTN	Myostatin	+
43	NODAL	Nodal homolog (mouse)	+
44	OSM	Oncostatin M	+
45	TGFB2	Transforming growth factor, beta 2	+
46	THPO	Thrombopoietin	−
47	VEGFA	Vascular endothelial growth factor A	+
TNF superfamily
48	CD40LG	CD40 ligand	−
49	FASLG	Fas ligand (TNF superfamily, member 6)	−
50	LTA	Lymphotoxin alpha (TNF superfamily, member 1)	−
51	LTB	Lymphotoxin beta (TNF superfamily, member 3)	+
52	TNF	Tumor necrosis factor	+
53	TNFRSF11B	Tumor necrosis factor receptor superfamily, member 11b	+
54	TNFSF10	Tumor necrosis factor (ligand) superfamily, member 10	+
55	TNFSF11	Tumor necrosis factor (ligand) superfamily, member 11	−
56	TNFSF13B	Tumor necrosis factor (ligand) superfamily, member 13b	+
Interleukins
57	IL1A	Interleukin 1, alpha	+
58	IL1B	Interleukin 1, beta	+
59	IL1RN	Interleukin 1 receptor antagonist	+
60	IL2	Interleukin 2	+
61	IL3	Interleukin 3 (colony-stimulating factor, multiple)	−
62	IL4	Interleukin 4	−
63	IL5	Interleukin 5 (colony-stimulating factor, eosinophil)	−
64	IL6	Interleukin 6 (interferon, beta 2)	+
65	IL7	Interleukin 7	+
66	IL8	Interleukin 8	+
67	IL9	Interleukin 9	−
68	IL10	Interleukin 10	−
69	IL11	Interleukin 11	+
70	IL12A	Interleukin 12A	+
71	IL12B	Interleukin 12B	−
72	IL13	Interleukin 13	−
73	IL15	Interleukin 15	+
74	IL16	Interleukin 16	−
75	IL17A	Interleukin 17A	−
76	IL17F	Interleukin 17F	−
77	IL18	Interleukin 18 (interferon-gamma-inducing factor)	+
78	IL21	Interleukin 21	−
79	IL23A	Interleukin 23, alpha subunit p19	+
80	IL22	Interleukin 22	−
81	IL24	Interleukin 24	−
82	IL27	Interleukin 27	+
Cytokines
83	ADIPOQ	Adiponectin, C1Q and collagen domain containing	−
84	IFNG	Interferon, gamma	−