Long Noncoding RNA MIR4697HG Promotes Cell Growth and Metastasis in Human Ovarian Cancer

Figure 6

Knockdown of MIR4697HG decreased the levels of MMP-9, phosphorylated ERK, and AKT in SKOV3 cells. SKOV3 cells with (shRNA group) or without (NC group) MIR4697HG knockdown were subject to protein extraction. The extracted proteins were then assayed using western blot analysis of matrix metalloproteinase 9 (MMP-9), ERK (phosphorylated or not), and AKT (phosphorylated or not).