High PINCH1 Expression in Human Laryngeal Carcinoma Associates with Poor Prognosis

Table 2

Expression of focal adhesion proteins α- and β-parvin in human laryngeal cancer in relation to clinical and pathological parameters.

		α-Parvin				value	β-Parvin				value
		Low; (n, %)		High; (n, %)			Low; (n, %)		High; (n, %)
Age	≤60	12	34.3%	23	65.7%	0.142	16	45.7%	19	54.3%	0.251
	>60	7	18.9%	30	81.1%		12	32.4%	25	67.6%
Location	Glottis	11	25.6%	32	74.4%	0.649	15	34.9%	28	65.1%	0.286
	Supraglottis	8	29.6%	19	70.4%		13	48.1%	14	51.9%
	Subglottis	0	0.0%	2	100.0%		0	0.0%	2	100.0%
Grade	Grade I	2	15.4%	11	84.6%	0.484	5	38.5%	8	61.5%	0.997
	Grade II	15	30.6%	34	69.4%		19	38.8%	30	61.2%
	Grade III	2	20.0%	8	80.0%		4	40.0%	6	60.0%
N	No	14	26.4%	39	73.6%	0.993	19	35.8%	34	64.2%	0.380
	N1–3	5	26.3%	14	73.7%		9	47.4%	10	52.6%
Stage	I	0	0.0%	1	100.0%		0	0.0%	1	100.0%
	II	1	25.0%	3	75.0%		3	75.0%	1	25.0%
	III	6	24.0%	19	76.0%	0.685	11	44.0%	14	56.0%	0.386
	IV	12	28.6%	30	71.4%		14	33.3%	28	66.7%

Statistical analyses were performed by nonparametric tests, and was considered statistically significant. Lymph node (N) metastasis and stage were determined based on TNM, 7th edition [33].