Positive Association between TGFB1 Gene and Susceptibility to Idiopathic Scoliosis in Bulgarian Population

Table 1

Genotype and allele distribution in different subgroups of idiopathic scoliosis.

Group		Genotypes,			Alleles,
		TT	TC	CC	T	C
General (, )	Cases	64	51	12	179	75
	Controls	82	126	46	290	218
AIS (, )	Cases	47	42	8	136	58
	Controls	82	126	46	290	218
JIS (, )	Cases	15	8	3	38	14
	Controls	82	126	46	290	218
FIS (, )	Cases	16	17	1	49	19
	Controls	82	126	46	290	218
NFIS (, )	Cases	48	34	11	130	56
	Controls	82	126	46	290	218
Males (, )	Cases	13	10	2	36	14
	Controls	20	22	8	62	38
Females (, )	Cases	51	40	11	142	62
	Controls	63	103	38	229	179

AIS—adolescent idiopathic scoliosis; JIS—juvenile idiopathic scoliosis; FIS—familial idiopathic scoliosis; NFIS—nonfamilial idiopathic scoliosis; —number of genotypes or alleles; —number of cases; —number of controls.