Positive Association between TGFB1 Gene and Susceptibility to Idiopathic Scoliosis in Bulgarian Population

Table 2

Inheritance models in different subgroups of idiopathic scoliosis.

Group	Genetic model	value	OR (95% CI)
General	Codominant	0.0020	2.99 (1.46–6.11)
	Recessive	0.0006	2.13 (1.38–3.29)
	Dominant	0.0265	2.12 (1.08–4.16)
	Allelic	0.0003	1.79 (1.30–2.47)
AIS	Codominant	0.0036	3.30 (1.43–7.57)
	Recessive	0.0049	1.97 (1.22–3.18)
	Dominant	0.0219	2.46 (1.12–5.43)
	Allelic	0.0016	1.76 (1.24–2.51)
JIS	Codominant	0.1189	2.80 (0.77–10.2)
	Recessive	0.0157	2.86 (1.26–6.50)
	Dominant	0.4427	1.69 (0.49–5.89)
	Allelic	0.0258	2.04 (1.08–3.86)
FIS	Codominant	0.0122	8.98 (1.15–69.9)
	Recessive	0.1218	1.86 (0.90–3.84)
	Dominant	0.0241	7.3 (0.97–54.74)
	Allelic	0.0251	1.94 (1.11–3.39)
NFIS	Codominant	0.0170	2.45 (1.16–5.17)
	Recessive	0.0010	2.24 (1.38–3.63)
	Dominant	0.1615	1.65 (0.81–3.34)
	Allelic	0.0022	1.75 (1.22–2.50)
Males	Codominant	0.4508	2.6 (0.48–14.23)
	Recessive	0.4596	1.63 (0.62–4.27)
	Dominant	0.4804	2.19 (0.43–11.2)
	Allelic	0.2760	1.58 (0.75–3.29)
Females	Codominant	0.0072	2.80 (1.30–6.01)
	Recessive	0.0011	2.24 (1.37–3.65)
	Dominant	0.0778	1.89 (0.92–3.88)
	Allelic	0.0013	1.79 (1.25–2.56)

AIS—adolescent idiopathic scoliosis; JIS—juvenile idiopathic scoliosis; FIS—familial idiopathic scoliosis; NFIS—nonfamilial idiopathic scoliosis; p—probability value; OR—odds ratio; CI—confidence interval.