Prognostic Significance of Cyclins A2, B1, D1, and E1 and CCND1 Numerical Aberrations in Oral Squamous Cell Carcinomas
Table 1
Patient characteristics ().
Factor
Group
N (%)
Gender
Female
15 (22.4%)
Male
52 (77.6%)
Age (mean age: 59 ± 12.6 years)
<59 years
33 (49.3%)
≥59 years
34 (50.7%)
Location
Tongue
28 (41.8%)
Floor of the mouth
20 (29.9%)
Gingiva
7 (10.4%)
Retromolar trigone
4 (6.0%)
Hard palate
5 (7.5%)
Buccal mucosa
3 (4.5%)
Tumour size
T1
22 (32.8%)
T2
27 (40.3%)
T3
6 (9.0%)
T4
12 (17.9%)
N status
N0
46 (68.7%)
N1
11 (16.4%)
N2
10 (14.9%)
Stage
I
21 (31.3%)
II
20 (29.9%)
III
11 (16.4%)
IV
15 (22.4%)
Treatment
SG
49 (73.1%)
SG + RT
18 (26.9%)
Tumour grade
G1
34 (50.7%)
G2
29 (43.3%)
G3
4 (6%)
Margin status
Free of tumour
54 (85.7%)
With tumour
9 (14.3%)
Vascular invasion
Absent
62 (92.5%)
Present
5 (7.5%)
Perineural permeation
Absent
56 (83.6%)
Present
11 (16.4%)
SG: surgery; RT: radiotherapy (consisting in adjunctive external-beam radiotherapy, 55-66Gy). Patients were excluded if they had undergone radiotherapy or chemotherapy prior to surgery. None of the included patients received molecular therapies against EGFR or other proteins. Not available in 4 cases. Table 1 is reproduced from Monteiro et al. [16] (under the Creative Commons Attribution License/Public Domain).
