Loss of BRCA1 Spontaneously Induces the Tumorigenesis in Lacrimal Gland

Figure 2

Identification of lacrimal gland tumors in Brca1^co/coMMTV-cre mice. (a–c) Low-power view of H&E-stained sections of the 16 (a), 17 (b), and 9 (c) months of age cases of retrobulbar tumors (asterisks) separated by skeletal muscles (arrows) in the eyeballs (E). Nonneoplastic lacrimal glands (N) adjacent to the tumors are evident. The panels at the right are magnifications of the boxed areas in the adjacent panels. Scale bars: 1 mm.

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