LncRNA LOXL1-AS1 Promotes the Proliferation and Metastasis of Medulloblastoma by Activating the PI3K/AKT Pathway

Figure 1

lncRNA LOXL1-AS1 was highly expressed in medulloblastoma. (a) qRT-PCR analysis of LncRNA LOXL1-AS1 in 50 cases of clinical medulloblastoma as well as their adjacent normal tissues. (b) The paired expression of LOXL1-AS1 was shown in the 50 cases. (c) All the 50 cases were subgrouped as T1, T2, T3, and T4 based on the tumor size. Relative level of LOXL1-AS1 in T3 and T4 cancerous tissues was significantly higher than that in T1 and T2 tissues. (d) qRT-PCR analysis of the relative level of LOXL1-AS1 in 5 medulloblastoma cell lines. The level of LOXL1-AS1 in the D458 cells was set as 1. LOXL1-AS1 levels in other cell lines were normalized to those in D458 cells. The p value for each comparison was indicated in each panel.

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