GTSE1, CDC20, PCNA, and MCM6 Synergistically Affect Regulations in Cell Cycle and Indicate Poor Prognosis in Liver Cancer

Figure 5

Association between 3 DEGs regulating cell cycle and survival of liver cancer patients. (a) Pearson’s pairwise correlation plots of the expression level of MCM6, CDC20, and PCNA vs GTSE1. (b) Protein interaction network and interaction scores among GTSE1, MCM6, CDC20, and PCNA. (c–d) The Kaplan-Meier curves of overall survival (OS) stratified by altered expression of MCM6 (a), CDC20 (b), and PCNA (c) gene from datasets GSE14520, TCGA-LIHC, and ICGC-LIRI-JR.