Research Article
Aberrant Expression of Folate Metabolism Enzymes and Its Diagnosis and Survival Prediction in Ovarian Carcinoma
Table 3
Performance of FOLR1, DHFR, and MTRR in the differential diagnosis drug-resistant cases from ovarian cancer patients.
| Groups | Sensitivity | Specificity | Accurate | Youden index | True positive | True negative | False positive | Flase negative |
| FOLR1 | 88.2% | 55.2% | 76.2% | 43.4% | 45 | 16 | 13 | 6 | DHFR | 69.0% | 62.7% | 65.0% | 31.7% | 20 | 32 | 19 | 9 | MTRR | 44.8% | 92.2% | 75.0% | 37.0% | 13 | 47 | 4 | 16 | FOLR1+DHFR+MTRR | 82.1% | 84.6% | 83.8% | 66.8% | 23 | 44 | 8 | 5 |
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