Kaempferol Promotes Apoptosis While Inhibiting Cell Proliferation via Androgen-Dependent Pathway and Suppressing Vasculogenic Mimicry and Invasion in Prostate Cancer

Figure 5

Kaempferol suppresses mRNA expression of AR target gene in LNCaP cells in the presence of DHT. (a) Kaempferol suppresses PSA mRNA expression by 48.25% at 5 μM, 68.62% at 10 μM, and 81.27% at 15 μM. (b) Kaempferol suppresses TMPRSS2 mRNA expression by 49.14% at 5 μM, 71.67% at 10 μM, and 79.48% at 15 μM. (c) Kaempferol suppresses TMEPA1 mRNA expression in qPCR by 41.45% at 5 μM, 58.06% at 10 μM, and 78.12% at 15 μM (). , compared with cells without kaempferol and DHT.

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