Downregulation of PTPRK Promotes Cell Proliferation and Metastasis of NSCLC by Enhancing STAT3 Activation

<div>PTPRK is frequently underexpressed in NSCLC with lymph node (LN) metastasis. (a) PTPRK mRNA expression was quantified by qRT-PCR in 30 lung tumors with non-lymph node metastasis and 16 tumors with lymph node metastasis. (b) qRT-PCR analysis of PTPRK expression levels in one normal human bronchial epithelial cell (16HBE) and seven NSCLC cell lines, and expression levels were all normalized to 16HBE.</div>

Analytical Cellular Pathology

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Figure 1

Figure 1: Downregulation of PTPRK Promotes Cell Proliferation and Metastasis of NSCLC by Enhancing STAT3 Activation 